CORDIS Project
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This research focuses on microtubule plus-end tracking proteins and their role in cellular processes. It aims to understand the molecular mechanisms of these proteins and identify small molecules that can modulate their interactions, potentially leading to new cancer therapies.
Microtubule plus-end tracking proteins (+TIPs) comprise a structurally and functionally diverse family of modular proteins that preferentially accumulate at microtubule (MT) growing ends.
There, they regulate MT dynamics and mediate the anchorage of MTs to many other different cellular structures to control fundamental cellular processes including cell division, intracellular transport, cell adhesion and motility, and cell organization. +TIPs have a remarkable ability to form dynamic networks wh…
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