CORDIS Project
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This project focuses on the CRISPR system in bacteria, exploring its role in gene regulation and defense against viruses. It aims to uncover its mechanisms and potential applications in biotechnology and ecological systems.
A novel type of defense system was recently identified in bacteria: the CRISPR array and its associated gene products (Cas).
The system inserts short DNA sequences, called spacers, derived from foreign nucleic acid molecules in between direct repeats, thus forming the CRISPR array.
The transcribed spacers eventually serve as molecular guides for Cas proteins that monitor and destroy nucleic acids having sequences similar to those spacers.
Thorough mapping of the functional components and regulat…
TEL AVIV UNIVERSITY
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