CORDIS Project
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ECMAP focuses on understanding fibrosis through a novel approach that mimics dynamic tissue interactions. By studying focal adhesion kinase signaling under mechanical forces, it aims to enhance drug discovery and monitoring of fibrosis.
Fibrosis, characterized by tissue stiffening and altered FAK signaling patterns, is highly prevalent in Europe and places a significant financial burden on our healthcare system.
However effective treatments are hampered by the lack of accurate disease models.
While most of our disease understanding comes from studying cells under static conditions, in vivo cell interactions are far from static, leading to inconsistencies between lab models, suggesting that tissue stiffness alone drives fibrosi…
QUEEN MARY UNIVERSITY OF LONDON
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