CORDIS Project
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This project investigates how multidrug-resistant Escherichia coli, particularly those producing Extended Spectrum β-Lactamases, colonize the gut without antibiotics. By studying various clones in mice, the research aims to uncover the genetic factors that contribute to their success and explore alternative treatment s…
The rise of multidrug-resistant bacteria limits the options to treat critically ill patients.
In 2015, Escherichia coli producing Extended Spectrum β-Lactamases (ESBL) were the leading cause of death attributable to antibiotic resistant bacteria in Europe.
The failure to address these infections using standard antibiotherapy calls for better understanding of how these bacteria evolve in order to develop new treatments.Presence of resistance and virulence genes correlates with high prevalence in…
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