CORDIS Project
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This study focuses on understanding the physiological mechanisms behind activity-related dyspnea in patients with pulmonary arterial hypertension. It aims to explore how respiratory muscle function and lung mechanics contribute to exercise limitations and poor quality of life.
Activity-related dyspnea appears to be the earliest and dominant symptom limiting exercise in the majority of patients afflicted by pulmonary arterial hypertension.
This symptom progresses relentlessly with time leading invariably to avoidance of activity with consequent skeletal muscle deconditioning and poor perceived quality of life.
Unfortunately, effective management of this disabling symptom awaits a better understanding of its underlying physiology. A growing body of evidence have high…
UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6
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