CORDIS Project
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This project aims to explore the structural mechanisms of the epidermal growth factor receptor (EGFR) using Nuclear Magnetic Resonance (NMR). By investigating how various cofactors influence EGFR activation, the research seeks to contribute to the development of new therapeutic agents for diseases like cancer.
The epidermal growth factor receptor (EGFR) is a key player in many biological responses and its aberrant function is associated with numerous diseases, including a number of cancers.
Despite the significant benefits of anti-EGFR agents in some tumours, many challenges remain in the improvement of EGFR-targeted therapies.This proposal targets cofactors in the EGFR signalling that, so far, were not exploited therapeutically and hence may not only contribute to the global effort in the understandi…
HEINRICH-HEINE-UNIVERSITAET DUESSELDORF
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