CORDIS Project
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This project focuses on understanding genetic factors contributing to cardiovascular and metabolic diseases using rat models. By sequencing the genomes of specific rat strains, researchers aim to identify and study gene variants that influence disease phenotypes, ultimately translating findings to human health.
Recent genetic studies have identified hundreds of susceptibility genes for common human diseases but genetic effects are small and identifying underlying mechanisms remains challenging.
Rodent models offer significant advantages for analysis of disease phenotypes.
Advances in genome resources and gene targeting have increased the attractiveness of the rat model for genetic studies but progress has been hampered by absence of relevant rat genome sequences.We recently sequenced the genome of the…
THE UNIVERSITY OF EDINBURGH
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IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom, LONDON
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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