CORDIS Project
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This project explores the genetic factors influencing longevity using the yeast model organism. It aims to identify quantitative trait loci associated with lifespan variation and understand the interaction of genetic and environmental factors on aging.
Ageing is the highest risk factor for a large number of diseases and yet surprisingly little is known about the underlying molecular mechanisms.
Ageing is a classical complex trait affected by both the genetic background and the environment, and varies quantitatively among individuals.
Identifying the causal genetic variants underlying variation in longevity is a major challenge. I propose to use the budding yeast, Saccharomyces cerevisiae, to identify quantitative trait loci (QTLs) contributing…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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