CORDIS Project
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The ELEGANCE project investigates the effects of gut microbiota metabolites on neuroinflammation and oxidative stress in brain cells derived from individuals with Attention Deficit Hyperactivity Disorder. By studying these interactions, the project aims to identify potential new drug targets and treatment strategies fo…
The pathophysiology of the most frequent neurodevelopmental disorder in the world, Attention Deficit Hyperactivity Disorder (ADHD), is influenced by the interaction of genetic and environmental risk factors.
Studies have been indicating the association between ADHD and changes in the microbiota-gut-brain axis (MGBA), which may cause neuroinflammation, and subsequent microglial activation, secretion of cytokines and oxidative stress in the central nervous system.
However, the precise mechanisms r…
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
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