CORDIS Project
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ELGN-GI is a novel drug designed to stimulate gut maturation in preterm infants, facilitating a quicker transition to oral nutrition. This treatment aims to improve health outcomes by reducing dependency on intravenous nutrition and associated risks.
Around 10% babies are born preterm, and premature birth is the 1st cause of new-born deaths.
Preterm infants are born with an underdeveloped gastrointestinal (GI) tract, causing intestinal malabsorption.
At the first weeks of life, adequate nutrition is critical for brain and vital organ development, so infants are placed on central line nutrition until their GI is capable of absorbing sufficient nutrition.
However, central line nutrition is inadequate for critical growth and poses life-threaten…
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