CORDIS Project
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This project investigates the genetic basis of longevity by studying rare genetic variants in long-lived individuals. Using advanced gene editing techniques, it aims to identify mechanisms that promote healthy aging and develop potential therapeutic compounds to enhance lifespan and health in the general population.
Advancing age is the major risk factor for many serious illnesses, including cancer, cardiovascular disease, and dementia.
The rising number of older individuals is thus causing a major burden of ill health.
However, individuals that reach an exceptional old age often seem to escape or delay age-related diseases, and part of this trait seems to be encoded in their genome.
Hence, by studying the genome of long-lived individuals, we may be able to identify mechanisms that could be targeted for hea…
Leiden University Medical Center
ACADEMISCH ZIEKENHUIS LEIDEN
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