CORDIS Project
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This project investigates the mechanisms behind dopaminergic neuron degeneration in Parkinson’s Disease using the model organism Caenorhabditis elegans. It aims to identify potential therapeutic targets and novel causes of neuronal cell death through high-throughput genetic screening and analysis.
BACKGROUND:Parkinson’s Disease, characterized by the progressive degeneration of dopaminergic neurons, afflicts millions of people.
Yet, no effective therapeutic strategies are available.This work uses Caenorhabditis elegans to study dopaminergic degeneration. C. elegans is a small nematode, highly amenable to genetics and high-throughput approaches, with a simple nervous system that is highly conserved at the level of gene expression and pathology with humans.
This study also utilizes a mutant…
UNIVERSITETET I STAVANGER
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