CORDIS Project
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This project focuses on understanding DNA methylation's role in mammalian embryonic development. It aims to develop innovative methods for single-cell analysis to investigate how cell-specific methylation patterns influence gene regulation and cell states.
DNA methylation is essential for normal mammalian development.
While seminal work has provided tremendous insight into the dynamic regulation of DNA methylation throughout embryogenesis, comprehensive understanding of how cell-specific methylation programs are established and maintained, and how they are involved in defining cell states in vivo through regulation of target genes, remains a formidable task.
Revolutionary technologies now offer unprecedented opportunities for understanding the fun…
WEIZMANN INSTITUTE OF SCIENCE
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