CORDIS Project
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This project investigates how neuronal signals interact with lymphatic systems in the intestine to regulate immune responses. By studying immune cell movement and signaling in Peyer's patches, it aims to uncover mechanisms that could lead to new treatments for inflammatory bowel diseases.
The intestine hosts a vast neuronal system, a large population of immune cells, diverse microbiota, and a complex blood and lymphatic network.
The intestinal lymphatic network comprises vessels and lymphoid organs, called Peyer’s patches (PPs), that together play important roles in dietary fat absorption, mucosal immune responses and trafficking of immune cells to the rest of the body.
This intestinal immune cell trafficking is key in gut-to-organ communication, and its disruption leads to immun…
UNIVERSIDADE CATOLICA PORTUGUESA
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