CORDIS Project
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This project aims to investigate beneficial mutations in the filamentous fungus Aspergillus nidulans to understand their role in adaptive evolution. It focuses on how these mutations interact and affect fitness, providing insights into evolutionary biology.
Understanding the properties of beneficial mutations is essential for a better understanding of adaptive evolution, since these mutations are the fuel of adaptation.
Not only their individual fitness properties are important, but also their combined effect on fitness, which may deviate from the additive or multiplicative expectation that is often assumed in population genetic models.
For instance, if the sign of the fitness effect of mutations (i.e. positive or negative) depends on the presence…
WAGENINGEN UNIVERSITY
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