CORDIS Project
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This project focuses on developing new catalysts for radical chemistry that enable controlled hydrogen atom transfer with enantioselectivity. It aims to create chiral building blocks for synthetic chemistry and enhance the modification of pharmaceuticals through stereochemical editing.
Chemical reactions, broadly speaking, can be mechanistically classified into two distinct types – those in which the electrons move singly and those in which they move in pairs, referred to as ‘radical reactions’ and ‘ionic reactions’ respectively.
The remarkable volume of attention now being focused on radical reactions, due to the popularisation of photoredox catalysis, underscores a long-standing challenge within the field of radical chemistry – that of controlling enantioselectivity.
This pr…
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