CORDIS Project
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This project investigates the mechanisms of endothelial dysfunction in diabetic retinopathy, focusing on how interactions between leukocytes and endothelial cells, as well as local inflammatory responses, affect endothelial health. It aims to uncover pathways that could lead to new treatments for this serious complicat…
Diabetic retinopathy (DR) is a major cause of blindness in adults and the underlying pathophysiology includes endothelial dysfunction.
Endothelial dysfunction is a perturbation of endothelial homeostasis including changes in endothelial barrier integrity, alterations of the endothelial cell surface, which becomes proinflammatory and mediates increased leukocyte adhesion and changes in endothelial survival functions.
Endothelial dysfunction is regulated by an intimate crosstalk of the endothelium…
TECHNISCHE UNIVERSITAET DRESDEN
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