CORDIS Project
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This project investigates the role of specific proteins in synaptic plasticity, focusing on how they regulate the trafficking of neurotransmitter receptors in response to neuronal activity. Understanding these mechanisms may shed light on cognitive deficits associated with mental disorders.
Synaptic connections in the brain are continuously remodelled in response to neuronal activity.
This process, known as synaptic plasticity, is widely seen as the cellular correlate of learning and memory.
Hence, it is expected that the elucidation of the mechanism underlying synaptic plasticity will help to understand the pathological alterations that result in cognitive deficits.It is being increasingly appreciated that synaptic transmission can be modulated by postsynaptic membrane trafficking…
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