CORDIS Project
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This project focuses on engineering biosensors that can detect metastatic cancer cells by responding to specific molecular indicators. It aims to enhance the immune system's ability to target and eliminate these cells during their vulnerable stages of migration.
Directional movement of cells in response to environmental cues (e.g. chemotaxis) is essential throughout biology, and the membrane receptors that initiate cell migration offer a key opportunity for modulation by synthetic biologists.
The design of chemotactic receptor biosensors for metastatic markers has the potential to expand the immune system’s spectrum of actions.
Metastatic cancers are extremely lethal, and tumor cells that escape to seed a secondary tumor in a distant organ often escape…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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