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ENLIGHT aims to enhance our understanding of Alzheimer's disease by investigating the molecular mechanisms of Channelrhodopsin-2, a light-sensitive protein used in optogenetics. The project combines advanced simulations to develop next-generation tools for studying brain function and neurodegenerative diseases.
Alzheimer's disease is the most common form of dementia.
It affects millions of people and is expected to increase in the coming decades due to aging of the population.
Optogenetics combines optics and genetics to gain insight into brain function by genetically inserting light-sensitive transmembrane proteins into neurons.
Channelrhodopsin-2 (ChR2) is an ion channel protein that enables precise temporal control turning neurons on or off in response to light.
In vivo optogenetic experiments have…
KUNGLIGA TEKNISKA HOEGSKOLAN
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Switzerland, Lausanne
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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