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ENSYNC aims to create a synthetic cell that can evolve by producing and replicating functional RNA structures within lipid vesicles. The project focuses on developing a system for directed evolution, enabling the synthetic cells to adapt and proliferate based on genetic variations.
Can we construct a cell from non-living matter?
In search for answers, bottom-up synthetic biology has successfully encapsulated functional sets of biomolecules inside lipid vesicles, yet a “living” synthetic cell remains unattained. ENSYNC aims for a prototype of a synthetic cell that encompasses a fundamental characteristic of life, namely evolution.
My past work shows that DNA origami can achieve custom-engineered synthetic cellular parts, but the mere encapsulation of preformed parts conflic…
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
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