CORDIS Project
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This project investigates the role of alternative splicing in pancreatic beta cells, focusing on how it affects insulin secretion and cell survival in diabetes. By analyzing transcriptional networks and using various experimental models, the research aims to uncover mechanisms that could lead to new therapies and bioma…
Pancreatic beta cells are highly specialized cells that play a key role in maintaining glucose homeostasis by secreting insulin.
Dysfunction or loss of beta cells results in diabetes, a worldwide growing epidemic.
Extensive research has started to uncover the signals and transcriptional networks that control specification, differentiation and maturity of the different pancreatic cell lineages, and in particular of beta cells.
However, posttranscriptional regulation during pancreas development ha…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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