CORDIS Project
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This project investigates the processes leading to epilepsy using human brain organoids to model disease. It aims to identify biomarkers and drug targets for preventing epileptogenesis, focusing on developing effective treatments for drug-resistant epilepsy.
Epilepsy is one of the most common neurological disorders, yet current treatments fail to prevent seizures in more than a third of cases (~37%).
Most drug targets focus on seizure suppression; however, these are symptoms of abnormal developmental changes in the neural network.
The processes that give rise to epileptic brain regions are summarized by the concept of epileptogenesis.
Therefore, preventing epileptogenesis is critical for long-lasting seizure freedom.
Studying epileptogenesis is chal…
INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
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