CORDIS Project
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This project seeks to reverse epigenetic changes in cancer stem cells to inhibit tumor growth and recurrence. It focuses on developing in vitro models to study differentiation and identify potential therapeutic targets for pediatric brain tumors.
I aim to develop methods to reverse epigenetic anomalies in cancer stem cells (CSCs) to switch off the unlimited cell division and cancer growth and to understand the involvement of epigenetics in tumour development and recurrence.
Epigenetic alterations are observed at the earliest stages of neoplasia within stem cells.
Importantly, the alterations are reversible and can potentially be “treated”.
In children, brain tumours are the leading cause of cancer-related mortality and morbidity.
There a…
UGOT - GOETEBORGS UNIVERSITET/UNIVERSITY OF GOTHENBURG
GOETEBORGS UNIVERSITET
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