CORDIS Project
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This project investigates how germ cell identity is regulated in vertebrates, specifically using zebrafish as a model. It focuses on the interplay between epigenetic control in the nucleus and translational regulation in the cytoplasm to understand germ cell differentiation and its implications for fertility and tumor…
Germ cells have unique role in development.
They are the only cells required for the transmission of genetic material from generation to generation in sexually reproducing organisms.
This makes them pivotal for the survival of species and ultimately for the propagation of life.
Although germ cells undergo extensive cellular differentiation during gametogenesis, they are protected from somatic reprogramming.
This requires precise control of transcriptional programs, misregulation of which leads t…
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