CORDIS Project
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This project focuses on generating specific antibodies to detect epitranscriptomic modifications in RNA, which are crucial for understanding gene regulation. The innovative immunization platform aims to produce high-affinity antibodies that can enhance research in molecular biology and disease contexts.
Epitranscriptomic modifications constitute specific marks in mRNA that regulate gene expression.
Identification ofepitranscriptomic modifications requires next generation sequencing analyses and specific validation, processes that are cumbersome and time consuming.
Furthermore, while some modifications are straightforward to identify, as they cause specific base changes (like RNAediting), most are only detectable either through chemical means (requiring large quantities of material) or by immuno…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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Germany, MAINZ
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
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