CORDIS Project
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This project explores the role of non-coding RNA in regulating gene expression and epigenetic modifications in yeast. It aims to identify and characterize unstable non-coding RNAs that influence transcriptional silencing and chromatin dynamics.
Our project is to understand the role of non coding (nc)RNA in the regulation of epigenetic landscape and gene expression. RNA interference pathway is absent in the budding yeast but recent works from our laboratory showed the existence of an original ncRNA-dependent pathway that controls gene expression in S. cerevisiae.
We characterized a cryptic unstable ncRNA mediating the transcriptional silencing of the transposon Ty1 through histone methylation.
Furthermore, unpublished data suggest the e…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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