CORDIS Project
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This project aims to understand the progression of non-alcoholic fatty liver disease by examining the role of immune cells and epigenetic modifications. It seeks to identify how these factors influence inflammation and potential therapeutic strategies for liver disease.
Non-alcoholic fatty liver disease (NAFLD) is a rapidly growing clinical problem, affecting a third of the European population.
The transition of hepatic fat accumulation to inflammation is the key event taking place in the progression of NAFLD.
This is controlled by a number of inflammatory and immune pathways including the activity of Natural Killer (NK) and Natural Killer T (NKT) cells.
Progression from hepatic lipid deposition to inflammation and cirrhosis also follows a substantially variabl…
KOC UNIVERSITY
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