CORDIS Project
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This project explores how environmental contaminants affect the epigenetic landscape of the earthworm Lumbricus rubellus, influencing gene expression and phenotypic plasticity. It aims to establish a model for understanding the relationship between epigenetics and environmental stressors.
It has been established that the epigenetic landscape (cytosine methylation, histone modification and non coding RNAs) impacts on the underlying genomic architecture thereby regulating the transcriptional machinery and modifying gene expression.
These elegant mechanisms of control influence tissue differentiation, organism life spam and can coordinate biochemical pathways responses to stressors such as UV light and elevated metal ion concentrations.
It is the aim of this project to test the over…
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