CORDIS Project
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This project focuses on enhancing the delivery of therapeutic molecules into cells by manipulating cell membrane permeability using pulsed electric fields. The goal is to develop a method to control cell susceptibility to these treatments for improved medical applications.
The integrity of the cell membrane, while essential for life of any biological cell, presents a barrier that sometimes needs to be transiently disrupted in order to deliver therapeutic molecules inside the cell.
High-intensity pulsed electric fields (PEFs) are used increasingly in medicine to achieve such increase in cell membrane permeability via a phenomenon called cell membrane electroporation. PEF-based clinical applications include gene therapy techniques, DNA vaccination, electrochemothera…
UNIVERZA V LJUBLJANI
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