CORDIS Project
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This project explores how alternative splicing is regulated during development and disease, particularly in cancer. It investigates the role of transcriptional enhancers in influencing splicing patterns, aiming to link enhancer activity to specific splicing outcomes.
Alternative splicing (AS) is a highly regulated process that is essential for creating the protein diversity required for correct cell-type specification.
Misregulation of AS programs can lead to cellular dysfunction, developmental problems and disease, such as cancer.
Understanding how alternative splicing is regulated during development and disease is therefore capital.Recent advances in the field have shown that, not only does AS regulation rely on the recruitment of various splicing factors…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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