CORDIS Project
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This project investigates the relationship between low levels of gonadal hormones, stress, and epigenetic changes that may contribute to the development of major depressive disorder. Using preclinical models, it aims to identify biomarkers that predict depression risk, enhancing understanding of mood disorders and pote…
Major depressive disorder afflicts ~16% of the population and is a leading cause of disability worldwide.
Classical antidepressants take weeks-to-months for clinical efficacy and only a sub-population of patients responds to treatment, highlighting the need for the development of novel rapid-acting and effective pharmacotherapies.
Hypogonadism, the decrease in the production of gonadal hormones occurring due to ageing or several other medical conditions, has been associated with an increased ris…
UNIVERSITY OF CYPRUS
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