CORDIS Project
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This project aims to identify host factors essential for the life cycle of human enteroviruses through a genome-wide CRISPR screen in intestinal cells. By understanding the interactions between host and virus, the research seeks to discover new drug targets for treating enterovirus infections.
Enterovirus infections are of public health concern as globally millions of people become infected each year.
Enteroviruses (HEV) are an assemblage of highly diverse positive-stranded RNA viruses that belong to the Picornaviridae family.
Four out of the 13 known enterovirus species are human pathogens, with poliovirus being the most prominent member.
The entry point for these viruses is the gastrointestinal or the respiratory tract from where they can spread to other organs and cause severe path…
KOBENHAVNS UNIVERSITET
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