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EVOaware is a platform designed to tackle therapeutic resistance in cancer by integrating advanced techniques like genome editing and high-throughput drug screening. It aims to accelerate the discovery of new cancer therapies by analyzing the evolutionary dynamics of tumors.
Solid tumours frequently develop resistance to therapies, leading to treatment failure.
This resistance arises from the complex interplay between heterogeneous cancer cell populations and their microenvironment, driving tumour evolution and local adaptation.
Current drug discovery pipelines fall short in addressing this complexity.
In this ERC-PoC, we will develop EVOaware, a groundbreaking platform that integrates genome editing, spatial barcoding, high-throughput drug screening, multimodal spa…
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
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