CORDIS Project
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This project aims to model tumor growth by incorporating evolutionary principles to better understand cancer development. It examines how mutations and selection pressures affect tumor dynamics using experimental and computational approaches.
Tumorigenesis is a form of somatic evolution, a topical subject given the advent of cancer genome sequencing.
However, we contend that some features of Darwinian evolution have been neglected when cancer is studied, as have some aspects of evolution that are special to cancers.
For example, tumours comprise an expanding population of cells, cancers must occur within a normal human lifespan, and genotypes detrimental to growth of the tumour as a whole may be selected.
These factors may render inv…
THE UNIVERSITY OF BIRMINGHAM
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United Kingdom, Oxford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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