CORDIS Project
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This project focuses on understanding the evolution of Escherichia coli, a significant pathogen, by analyzing genetic changes in a large cohort of healthy individuals. It aims to uncover the drivers of antibiotic resistance and virulence in this bacterium to inform better management strategies for infectious diseases.
Understanding the rapid adaptation of infectious pathogens is crucial to design better management policies and anticipate future changes.
Yet, existing models often fail to explain these dynamics. I will address this major challenge of evolutionary biology in the bacterial species Escherichia coli. E. coli is a commensal of the human gut and an opportunistic pathogen causing infections responsible for more than a million deaths worldwide per year. E. coli has rapidly evolved over the last four d…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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