CORDIS Project
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This project aims to understand how genomic sequences determine cell identity in the pallium across various vertebrate species. By utilizing advanced sequencing techniques and machine learning models, it seeks to uncover the regulatory logic of genes that dictate cell types, with potential applications in therapeutic d…
Vertebrate genomes consist of tens of thousands of genes and yet they produce only a limited number of stable cell types.
Our understanding of how cell types are encoded in the genome is still lacking.
The expression of genes is controlled by gene regulatory elements, which are evolutionarily much less conserved than genes are and can be located far away in the genome.
My main goal is to better understand how the genomic sequence underlies cell identity in the pallium across vertebrate species a…
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