CORDIS Project
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This project investigates the genetic and biological mechanisms behind the variability of human immune responses to microorganisms. By analyzing different populations and utilizing advanced genomic and bioinformatics techniques, it aims to uncover how genetic variants influence immune traits and their evolutionary sign…
Recent genome-wide association studies have successfully identified rare and common variants that correlate with complex traits.
However, they have provided us with little insight into the nature of the genetic, biological and evolutionary relationships underlying such complex phenotypes.
There is thus a growing need for approaches that provide a mechanistic understanding of how genetic variants function to impact phenotypic variation and why they have been substrates of natural selection.
One s…
INSTITUT PASTEUR
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