CORDIS Project
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This project assesses the risk of vaccines leading to resistant virus strains by studying human papillomavirus dynamics. It combines clinical data with evolutionary ecology to understand the impact of vaccination on viral evolution.
There is a threat that evolutionary responses can render vaccines ineffective, as illustrated by the emergence of the increasingly virulent Marek Disease Virus strains in poultry following vaccination campaigns.
Assessing the ‘evolution-proof’ nature of vaccines targeting human viruses is challenging because it requires an understanding of the epidemiology, the within-host ecology and the evolutionary potential of the virus.
To date, most investigations into the spread of vaccine-resistant strai…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER
France, Montpellier
Type: Research institute
Activity type: Research Organisations
SME: No
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