CORDIS Project
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The STAND UP project investigates age-related bone loss in humans and its evolutionary roots by comparing skeletal changes in humans, chimpanzees, and gorillas. It aims to identify epigenetic factors influencing osteoporosis, particularly in post-menopausal women, to better understand this global health issue.
Age-related bone loss in humans is widely documented and linked to the process of skeletal gracilization, evolved over the last 10 kyrs.
One explanation for the human susceptibility to bone loss during ageing is that osteoporosis is an unintended consequence of otherwise advantageous evolutionary adaptations.
However, the deeper evolutionary roots and potential epigenetic changes that underlie the biological mechanism of age-related bone loss in humans compared to other hominids are still not un…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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United States, Atlanta
Type: Research institute
Activity type: Research Organisations
SME: No
Italy, Bologna
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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