CORDIS Project
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This project investigates the role of a newly identified protein, PWWP Domain Interactor of Polycombs 1 (PWO1), in regulating gene expression through Polycomb Repressive Complex 2 (PRC2) in plants. It aims to explore how PWO-like proteins influence plant evolution and developmental processes using synthetic biology tec…
The Polycomb Group (PcG) proteins ensure the accuracy of developmental processes and maintain cellular identities in both plants and animals.
Among the PcG proteins, Polycomb Repressive Complex 2 (PRC2) establishes the repressive state of targeted genes by introducing the H3K27me3 epigenetic mark.
Recently, a novel PWWP DOMAIN INTERACTOR OF POLYCOMBS 1 (PWO1) protein has been identified as a recruiter and regulator of PRC2. PWO1 may also act as a mediator of PRC2 repression at the nuclear periph…
BIOLOGICKE CENTRUM AKADEMIE VID CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE
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