CORDIS Project
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This research aims to explore the effects of exercise on liver health, particularly in the context of non-alcoholic fatty liver disease (NAFLD). The project will investigate how exercise influences mitochondrial function and nicotinamide adenine dinucleotide (NAD) metabolism in the liver.
Non-alcoholic fatty liver disease (NAFLD) has become the most prevalent liver disease in industrialized countries, including Europe, and comprises a spectrum of disorders ranging from hepatic lipid accumulation (steatosis) to inflammation (non-alcoholic steatohepatitis, NASH) and fibrosis.
Pathogenic pathways leading from hepatic steatosis to NASH are still incompletely understood resulting in a lack of approved therapeutic options besides life style changes.
Physical activity is effective to pr…
THE UNIVERSITY OF BIRMINGHAM
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