CORDIS Project
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This project investigates the neuroprotective effects of bone marrow-derived stem cells on retinal ganglion cells, which are crucial for vision. It explores the potential of exosomes as a cell-free therapy to support RGC survival and regeneration in models of eye disease.
The death and dysfunction of retinal ganglion cells (RGC) is a major cause of blindness in traumatic and degenerative ocular disease.
For example, 60M people are affected by glaucoma with 4.5M becoming blind in both eyes, whilst optic neuritis affects 5/100,000 people and represents a significant problem for sufferers. RGC are the sole projection neurons and their axons make up the optic nerve, making them exquisitely sensitive to injury.
As CNS neurons are irreplaceable, neuroprotective strateg…
THE UNIVERSITY OF BIRMINGHAM
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United States, Washington D.C.
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SME: No
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