CORDIS Project
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ExoBBB focuses on developing advanced delivery systems for microRNAs to treat neurodegenerative diseases by enhancing their stability and targeting capabilities. Utilizing biocompatible nanoparticles, the project aims to improve the transport of therapeutic RNA across the blood-brain barrier to regulate gene expression…
MicroRNAs (miRs) are identified as significant regulators in modulating brain functions in central nervous system (CNS) disorders like Alzheimer’s disease (AD), Huntington’s and Parkinson’s disease (PD) and amyotropic lateral sclerosis.
Sustained delivery of miRNAs to brain could be an excellent strategy to regulate gene expressions affected in the progressive neurodegenerative diseases.
Highly biocompatible nanocarriers like extracellular vesicles (eg: exosomes) are an excellent choice as deliv…
CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO
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