CORDIS Project
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This project aims to develop a therapy using extracellular vesicles from stem cells to treat fistulas associated with Crohn's disease. By optimizing the production and delivery of these vesicles, the research seeks to improve treatment efficacy and patient outcomes.
Extracellular vesicles (EVs) from stem cells (SCs) may recapitulate the therapeutic effect of their mother cells in regenerative medicine while mitigating risks of uncontrolled replication, differentiation and vascular occlusion, offering off-the-shelf, storage and shelf-life gains.
Yet, the clinical translation of SC EV therapy is hampered by production, engineering and administration challenges.
Building on my preliminary results, ExocyTher aims at developing SC EV therapy through:(1) standard…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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