CORDIS Project
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The EXODUS project investigates how environmental factors trigger autoimmune diseases, particularly focusing on immune cell activation at epithelial surfaces. It aims to develop innovative genetic tools to trace immune cell behavior and activation states, enhancing our understanding of autoimmune responses in the centr…
The incidence of autoimmune diseases including multiple sclerosis is dramatically increasing.
While there is a genetically defined “bedrock” susceptibility to develop T cell mediated autoimmunity, environmental cues likely determine the threshold for disease development.
Yet, little is known on how environmental cues sensed at body/environment interfaces are translated into immunopathology in distant organs like the central nervous system (CNS).Here, we raise the hypothesis that immune cells mus…
KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
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