CORDIS Project
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This project examines the role of oviduct exosomes in improving embryo quality during in vitro fertilization in cattle. It aims to assess how these maternal signals affect embryo development and could enhance reproductive technologies in both cattle and potentially humans.
The current embryo in vitro culture conditions used in most laboratories of assisted reproductive technologies (ARTs) allow the embryo to develop to the blastocyst stage and to achieve pregnancy.
However, the quality of those embryos is suboptimal compared to the in vivo ones and the obtained pregnancy rates are low.
The lack of maternal signals, during the in vitro period has been postulated as a main reason for these suboptimal results.
There is increasing evidence of the role of the oviduct e…
UNIVERSITAT ZURICH
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