CORDIS Project
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This project aims to elucidate the role of the exosome complex in RNA degradation, a key process in gene expression regulation. By studying the interactions of the exosome with accessory proteins, it seeks to provide insights into RNA stability and cellular function.
Regulation of RNA stability is recognized as a widely used strategy to regulate protein abundance in time and space in all eukaryotes. RNA degradation regulates gene expression in various processes during development and differentiation and in changing physiological conditions.
Many elements of the RNA decay machinery have been identified, but details of their function remain elusive.The exosome is a multi-subunit exonuclease complex that functions in turnover, quality control and processing of…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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