CORDIS Project
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This project investigates how sensory visual experiences shape the development of neural circuits in the Xenopus visual system. By using advanced genetic engineering and computational methods, it aims to understand synaptic plasticity and its impact on motor behavior and neural connectivity.
During development, neuronal connectivity is initially established by genetically determined intrinsic factors, e.g. molecular cues and spontaneous activity, generating networks according to a ""best guess"" strategy.
However, with the appearance of sensory organs, external inputs will refine these connections, allowing adaptation to the environment.
In the Xenopus developing visual system, repetitive moving visual stimuli induce long lasting changes in the direction-sensitivity of some tectal…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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