CORDIS Project
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This project aims to understand ligand recognition in ionotropic glutamate receptors, which are crucial for brain function. By combining bioinformatics, phylogenetics, and mutagenesis, it seeks to reveal the molecular mechanisms underlying how different receptors recognize various ligands.
Molecular biology strives for the prediction of function, based on the genetic code.
Within neuroscience, this is reflected in the intense study of the molecular basis for ligand recognition by neurotransmitter receptors.
Consequently, structural and functional studies have rendered a profoundly high-resolution view of ionotropic glutamate receptors (iGluRs), the archetypal excitatory receptor in the brain.
But even this view is obsolete: we don’t know why some receptors recognize glutamate yet…
UNIVERSITETET I BERGEN
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Denmark, Kobenhavn
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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